This route lets you check out some iconic landmarks like the Erie Canal Museum or the historic city of Rochester. The quickest takes 8 hours 30 minutes and heads through Syracuse. There are two possible routes for this trip. However, breaking up your trip over a few days will give you the chance to experience all that the road trip has to offer, from the beautiful Catskills and Hudson Valley, to the awe-inspiring views of Syracuse and Rochester and the exhilarating rush of Niagara Falls. This means you could complete the trip in one day. You will cover the entire 500-mile route in about 8 hours 30 minutes – if you don't make unexpected stops along the way. The road trip from New York to Toronto is largely an Interstate drive that takes you through a number of cities. Bist/ How far is Toronto from New York, and how long will the road trip take? Comparison of road trip options between New York and Toronto Route